We discussed the evaluation and differential diagnosis of pineal tumors in adults, focusing on the pinocytomas.   Presenter: Dr Bountouris. Participants: Prof.Spyridonidis, Dr Liga, Dr Spyridis, Dr Lekka.

The excellent review from Zeieser and  Blazar on chronic GvHD published  in NEJM was discussed. Presenter: Prof. Spyridonidis Participants: Dr Liga, Dr Spyridis, Dr Lekka, Dr Bountouris

We discussed the central role of B cell activation in chronic GVHD and  discussed the results of ibrutinib in cGVHD which led to FDA approval. Presenter: Prof. Spyridonidis Participants. Dr Liga, Dr Spyridis, Dr Lekka, Dr Bountouris

The excellent review from Zeieser and  Blazar on acute GvHD published in  NEJM was discussed. Presenter: Prof. Spyridonidis Participants: Dr Liga, Dr Spyridis, Dr Lekka, Dr Bountouris

We reviewed a case of AML with 11q23 abnormality involving the MLL gene and discussed the indication for transplant.   Presenter: Prof. Spyridondis Particiaptns: Dr Liga, Dr Spyridis, Dr Lekka, Dr Bountouris  

We presented a retrospective study showing that from patients not  receiveing alllo-HCT at CR-1, at 10 years 16.6% of patients aged <60  years and 2.4% of those aged ≥60 years were alive and disease-free. This  disease-free AML group consisted predominantly of patients with  core-binding factor AML with t(8;21)(q22;q22) or  inv(16)(p13q22)/t(16;16)(p13;q22) and...

Human herpesvirus 6 as a possible cause of pleuropericardial effusion in patients with hematologic malignacies after allogeneic transplantation.   Presenter: Dr Lekka Participants: Prof.Spyridonidis, Dr Liga, Dr Spyridis, Dr Bountouris

The study from the French group with positive results in gene therapy for Transfusion dependent Thalassemia patients was presented. We discussed the ended of conditioning in these patients with busulphan. Furthermore we discussed the need of busulphan levels in specific patients (eg children, thalssemia...

We discussed a case of isolated CNS relapse of an ALL ph + after BMT.  Interestingly the CNS relapse revealed with an AML clone. We discussed  the current literature. We specifically reviewed the cases in Table 3 of the paper attached. Presenter: Prof. Spyridonidis Participants: Dr Liga, Dr...

Revised diagnosis and severity criteria for sinusoidal obstruction syndrome/veno-occlusive disease in adult patients: a new classification from the European Society for Blood and Marrow Transplantation Presenter: Dr Spyridis  Participants: Prof.Spyridonidis, Dr Liga, Dr Lekka, Dr Bountouris

If uncommon haplotype then a MUD search may be commited. Presenter: Prof.Spyridonidis Participants: Dr Liga, Dr Spyridis, Dr Lekka, Dr Bountouris

A patient of ours with hhv6 viremia reveled pleuritis and pericardial infusion. Dr Lekka reviewed the literature and presented two case reports with hhv6 associated pericarditis. Presenter: Dr Lekka Participants: Prof.Spyridonidis, Dr Liga, Dr Spyridis, Dr Bountouris

Έγινε παρουσίαση της Δημοσίευσης της εγκριτικής μελέτης του EPREX στο Leukemia 2018 και συζητηθηκε ο αλγοριθμος θεραπειας στα MDS low risk. Presenter: Prof. Spyridonidis Participants: Dr Liga, Dr Spyridis, Dr Aggelinas

Two retrospective studies from EBMT and CIBMTR verified that  conditioning intensity plays a role in BMT for AML. We discussed the  terms myeloablative, RIC, RTC, NMA, lymphodepleting. Dr. Spyridonidis  presented his new (EBMT) intensity index. Presenter: Prof. Spyridondis Participants: Dr Liga, Dr Spyridis, Dr Aggelinas

The antiviral prophylaxis for cytomegalovirus infection in allogeneic  hematopoietic cell transplantation was reviewed. Prophylaxis reduse CMV  reactivation and disease but has little effect on OS in older studies,  except the newly published letermovir study. We discussed our current practice. Presenter: Prof. Spyridonidis Participants: Dr Liga, Dr Spyridis, Dr Aggelinas

A transplantational research project showing that the combined Tx of CBU and  multiple allogeneic progenitors may facilitate early engraftment without  affecting the long term engraftment of the single CBU. Presenter:Prof.Spyridonidis Participants: Dr.Liga, Dr.Spyridis, Dr.Aggelinas

We discussed an excellent article published in NEJM regarding the clinical value of PDL1 expression. Presenter:Prof.Spyridonidis Participants: Dr.Liga, Dr.Spyridis, Dr.Aggelinas

The significance of HHV6 viremia was discussed. Presenter:Prof.Spyridonidis Participants:Dr.Liga, Dr.Spyridis, Dr.Aggelinas